/* AOD: copper = fat metabolism, teal = human trials, lilac = tissue research. */
.aod9604-dossier{--aod:#f1ae8d;--aod-human:#64d4bf;--aod-tissue:#b8a0f4}
html[data-mode=light] .aod9604-dossier{--aod:#a64e24;--aod-human:#087967;--aod-tissue:#7550ae}
.aod9604-dossier .dossier-section h2 em,.aod9604-dossier .receptor-caption{color:var(--aod)}
.aod9604-dossier .sema-signal-badge{color:var(--aod);border-color:var(--aod);font-size:21px}
.aod9604-dossier .lab-organ-tag.tag-skin{--tag-color:var(--aod)}.aod9604-dossier .lab-organ-tag.tag-pancreas{--tag-color:var(--aod-human)}.aod9604-dossier .lab-organ-tag.tag-joints{--tag-color:var(--aod-tissue)}

.aod-identity{display:grid;grid-template-columns:minmax(220px,.75fr) minmax(0,1.25fr);gap:clamp(28px,5vw,72px);align-items:center;border:1px solid var(--line);padding:clamp(24px,4vw,48px);background:radial-gradient(ellipse at 15% 30%,color-mix(in srgb,var(--aod) 9%,transparent),transparent 65%)}
.aod-fragment-art{display:flex;flex-direction:column;align-items:center;gap:18px;color:var(--aod);text-align:center}.aod-fragment-art>span{font-size:11px;letter-spacing:.13em}.aod-fragment-art strong{font-size:clamp(100px,12vw,160px);font-weight:400;line-height:1}.aod-chain{display:grid;grid-template-columns:repeat(8,1fr);gap:9px;max-width:100%;padding:16px}.aod-chain i{width:12px;height:12px;border:1px solid var(--muted);border-radius:50%;opacity:.45}.aod-chain i.fragment{background:var(--aod);border-color:var(--aod);opacity:1}.aod-fragment-art code{font-size:12px;letter-spacing:.03em;max-width:100%;overflow-wrap:anywhere}
.aod-summary-grid{display:grid;grid-template-columns:repeat(3,1fr);margin-top:32px;border-block:1px solid var(--line)}.aod-summary-grid article{padding:28px}.aod-summary-grid article+article{border-left:1px solid var(--line)}.aod-summary-grid h3{font-size:21px!important;color:var(--aod)}
.aod-fat-map{display:flex;align-items:center;justify-content:space-evenly;gap:28px;border-block:1px solid var(--line);padding:40px 25px;margin-bottom:20px;background:radial-gradient(ellipse at 25% 50%,color-mix(in srgb,var(--aod) 5%,transparent),transparent 65%)}
.aod-fat-cell{width:190px;height:170px;border:1px solid var(--aod);border-radius:45% 55% 50% 45%;position:relative;display:grid;place-items:center}.aod-fat-cell i{position:absolute;inset:18%;border:1px solid color-mix(in srgb,var(--aod) 35%,transparent);border-radius:50%;transform:translate(-14px,0)}.aod-fat-cell i:nth-child(2){inset:30%;transform:translate(30px,-20px)}.aod-fat-cell i:nth-child(3){inset:35%;transform:translate(20px,33px)}.aod-fat-cell i:nth-child(4){inset:39%;transform:translate(-40px,36px)}.aod-fat-cell strong{font-size:14px;background:var(--bg);padding:7px;z-index:1;font-weight:500}
.aod-fat-path,.aod-fat-result{display:flex;flex-direction:column;align-items:center;gap:14px;text-align:center}.aod-fat-path>span{color:var(--aod);font-size:17px}.aod-fat-path b{font-size:42px;font-weight:400;color:var(--aod)}.aod-fat-map small{color:var(--muted);font-size:12px;max-width:160px;line-height:1.6}.aod-fat-result>span{font-size:13px;color:var(--muted)}.aod-fat-result strong{color:var(--aod);font-size:23px;font-weight:500}.aod9604-dossier .sema-explainer{margin-top:32px}
.aod-evidence-timeline{display:grid;grid-template-columns:.85fr 1fr 1.2fr;border-block:1px solid var(--line)}.aod-evidence-timeline article{padding:30px 25px 20px}.aod-evidence-timeline article+article{border-left:1px solid var(--line)}.aod-evidence-timeline h3{font-size:24px!important;margin-top:24px!important}.aod-tag{font-size:11px;letter-spacing:.07em;line-height:1.7;color:var(--aod)}.aod-study-count{margin-top:24px;display:flex;gap:16px;align-items:center}.aod-study-count b{font-size:64px;font-weight:400;line-height:1;color:var(--aod)}.aod-study-count span{font-size:12px;line-height:1.7;color:var(--muted);max-width:95px}.aod-trial-main{background:linear-gradient(145deg,color-mix(in srgb,var(--aod-human) 7%,transparent),transparent 75%)}.aod-trial-main .aod-tag,.aod-trial-main .aod-study-count b{color:var(--aod-human)}
.aod-takeaway{margin:30px 0;padding:26px 30px;border-left:2px solid var(--aod-human);background:color-mix(in srgb,var(--aod-human) 4%,var(--surface))}.aod-takeaway p:last-child{margin-bottom:0}
.aod-two-col{display:grid;grid-template-columns:1fr 1fr;gap:0 42px}.aod-two-col article{padding:28px 0;border-top:1px solid var(--line)}.aod-two-col h3{font-size:24px!important}
.aod-cartilage-grid{display:grid;grid-template-columns:.6fr 1.4fr;align-items:center;gap:40px;padding:35px;border:1px solid var(--line);background:radial-gradient(ellipse at 15% 50%,color-mix(in srgb,var(--aod-tissue) 7%,transparent),transparent 65%)}.aod-joint-art{display:flex;flex-direction:column;align-items:center;gap:20px}.aod-joint-art svg{width:220px;max-width:100%;stroke:var(--muted);stroke-width:2}.aod-joint-art .cartilage{stroke:var(--aod-tissue);stroke-width:4}.aod-joint-art span{font-size:10px;letter-spacing:.07em;color:var(--aod-tissue);text-align:center}
.aod-pain-chart{margin:0 0 30px;border:1px solid var(--line);padding:clamp(22px,4vw,48px);background:linear-gradient(135deg,color-mix(in srgb,var(--aod-tissue) 6%,var(--surface)),var(--surface) 65%)}.aod-pain-chart h3{margin-top:20px!important}.aod-chart-bars{padding:25px 0}.aod-chart-bars>div:not(.aod-chart-axis){display:grid;grid-template-columns:110px minmax(0,1fr) 58px;align-items:center;gap:20px;margin:20px 0}.aod-chart-bars span,.aod-chart-bars b{font-size:14px;font-weight:500}.aod-chart-bars>div>div{height:16px;background:color-mix(in srgb,var(--line) 40%,transparent)}.aod-chart-bars i{height:100%;display:block;background:var(--aod-tissue)}.aod-chart-bars .control i{background:var(--muted);opacity:.65}.aod-chart-bars b{text-align:right}.aod-chart-axis{display:flex;justify-content:space-between;margin:0 78px 0 130px;color:var(--muted)}.aod-chart-axis span{font-size:11px}.aod-chart-conclusion{display:flex;gap:25px;align-items:center;padding:22px 0;margin-bottom:15px;border-block:1px solid var(--line)}.aod-chart-conclusion strong{font-size:30px;font-weight:400;color:var(--aod-tissue);white-space:nowrap}.aod-chart-conclusion span{font-size:15px;line-height:1.7;color:var(--muted)}
.aod9604-dossier .community-rows>article>span{overflow-wrap:anywhere}.aod-source-list{padding-left:24px}.aod-source-list li{font-size:14px;line-height:1.7;padding:14px 0;border-bottom:1px solid var(--line);overflow-wrap:anywhere}
@media(max-width:1000px){.aod-evidence-timeline{grid-template-columns:1fr}.aod-evidence-timeline article{padding:28px 0}.aod-evidence-timeline article+article{border-left:0;border-top:1px solid var(--line)}.aod-evidence-timeline .aod-trial-main{padding:28px 24px}.aod-study-count span{max-width:none}.aod-study-count{gap:24px}.aod-study-count b{font-size:56px}}
@media(max-width:800px){.aod-identity,.aod-cartilage-grid{grid-template-columns:1fr}.aod-summary-grid{grid-template-columns:1fr}.aod-summary-grid article{padding:25px 0}.aod-summary-grid article+article{border-left:0;border-top:1px solid var(--line)}.aod-two-col{grid-template-columns:1fr}.aod-cartilage-grid{padding:25px}.aod-joint-art svg{width:170px}}
@media(max-width:600px){.aod-fat-map{gap:12px;padding:30px 10px}.aod-fat-cell{width:105px;height:110px;flex-shrink:0}.aod-fat-cell strong{font-size:11px}.aod-fat-path>span{font-size:12px}.aod-fat-map small{font-size:10px;max-width:90px}.aod-fat-result strong{font-size:15px}.aod-fat-result>span{font-size:11px}.aod-fat-path b{font-size:30px}.aod-takeaway{padding:22px}.aod-chart-bars>div:not(.aod-chart-axis){grid-template-columns:68px minmax(0,1fr) 45px;gap:10px}.aod-chart-axis{margin-left:78px;margin-right:55px}.aod-chart-axis span{font-size:10px}.aod-chart-conclusion{gap:18px;align-items:flex-start;flex-direction:column}.aod-chart-conclusion strong{font-size:26px}.aod-chart-bars span,.aod-chart-bars b{font-size:12px}.aod-pain-chart{padding:24px 18px}}